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Anti-MSH6 Antibody, Recombinant Antibody

產(chǎn)品編號(hào):RMAP0E5M1
   
詢價(jià)

規(guī)格     100ug

產(chǎn)品名稱Anti-MSH6 Antibody, Recombinant Antibody
 
經(jīng)驗(yàn)證的應(yīng)用IHC
 
交叉反應(yīng)/
 
特異性/
 
免疫原/
 
制備方法/
 
來源Recombinant Antibody
 
純化Protein A purified
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài)Liquid
 
運(yùn)輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲(chǔ)存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
 
別稱/
 
背景信息MSH6 is a 160 kD protein which is involved in DNA mismatch repair (MMR) and recombination pathways, when heterodimerized with MSH2. Defects in mismatch repair systems can cause mutations and can cause DNA microsatellite sequences to become unstable. Immunohistochemical studies have reported that MSH6 is strongly expressed in the nucleus of cells in normal colonic epithelium, especially in crypts. Expression is also found in lymphocytes. Studies have also shown that MSH6 is expressed in gastric carcinomas and endometrial carcinomas. However, sometimes expression can be lost in some endometrial carcinomas and colonic carcinomas with microsatellite instability.

全稱/
 
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