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Anti-3-nitrotyrosine Antibody, Recombinant Antibody

產(chǎn)品編號:RPTMD2M1
   
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規(guī)格     100ug
 

產(chǎn)品名稱Anti-3-nitrotyrosine Antibody, Recombinant Antibody
 
克隆號
 
抗體亞型IgG
 
經(jīng)驗(yàn)證的應(yīng)用WB
 
交叉反應(yīng)all
 
特異性Recognizes 3-Nitrotyrosine

免疫原Nitrotyrosine
 
制備方法/
 
來源Recombinant Mouse IgG
 
純化Protein G聯(lián)合nitro-Tyr抗原多肽親和層析純化.
 
緩沖液Supplied in PBS, 50% glycerol and less than 0.02% sodium azide, PH7.4
 
偶聯(lián)物Unconjugated
 
狀態(tài):Liquid
 
運(yùn)輸方式This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended.
 
儲存條件This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

別稱nitro-Tyr, Nitro-Tyrosine
 
背景信息Nitric oxide (NO) is implicated in carcinogenesis, chronic infection, inflammation and neurodegeneration. High levels of both superoxide and nitric oxide in tissues interact to form peroxynitrite, a potent oxidant that can modify Tyr residues in proteins to form 3-nitro-tyrosine. Tyrosine nitration of mitochondrial manganese superoxide dismutase results in loss of enzymatic activity. The nitration of p53 at Tyr residues abolishes its capacity for binding to its DNA consensus sequence.

全稱/
 
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